Folic acid receptor-targeted human serum albumin nanoparticle formulation of cabazitaxel for tumor therapy
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Folic acid-functionalized human serum albumin nanocapsules for targeted drug delivery to chronically activated macrophages.
Activated synovial macrophages play a key role in Rheumatoid Arthritis (RA). Recent studies have shown that folate receptor beta (FRβ) is specifically expressed by activated macrophages. Therefore a folate-based nanodevice would provide the possibility of delivering therapeutic agents to activated macrophages without affecting normal cells and tissues. This study shows for the first time the so...
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ژورنال
عنوان ژورنال: International Journal of Nanomedicine
سال: 2018
ISSN: 1178-2013
DOI: 10.2147/ijn.s181296